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Furthermore, using the Illumina Infinium Human Methylation27 Bead Chip microarray, significant differences in methylation levels of CLDN16 , DDC , and NXT2 were observed in HD patients compared to controls (Zadel et al., 2018)

Sundstrom-Poromaa I, Smith DH, Gong QH, Sabado TN, Li X, Light A et al (2002)

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TUDCA mitigated aGVHD by reducing intestinal epithelial apoptosis and downregulating antigen presentation by non-hematopoietic cells, independently of microbiome changes and without compromising graft-versus-leukemia effects (61)
Improves cellular communications

M2-like characteristics in most TAMs enhance tumor growth, immunoevasion, and metastasis
