monthly b12 injections π. SAVE THE DATE!! π
Description
Rimonabant is a cannabinoid receptor 1 antagonist that became available for long-term treatment of obesity in the United Kingdom and other countries beginning in 2006 [27]
Unfortunately, studies on this topic have mainly focused on normalising serum B12 concentrations with oral supplementation and should be interpreted with caution since the specific goal of treatment in symptomatic B12 deficiency is alleviating symptoms, and NOT to normalize B12 concentrations in the blood

Alternatively, 1000mcg SC/MC can be given every day for 2-7 days, followed by maintenance treatment

Efficacy and tolerability of oral and intramuscular S-adenosyl-L-methionine 1,4-butanedisulfonate (SAMe) in the treatment of major depression: comparison with imipramine in 2 multicenter studies

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It works through a different mechanism (fat oxidation via beta-3 adrenergic receptors, not appetite suppression), and that mechanism produces gradual, subtle changes