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As used herein, the terms cell, cells, and a cell expressing NNMT (as used interchangeably herein) refer to one or cells, from any animal, which expresses NNMT, such as, without limitation, rat, mice, monkey, horse, dog, cat, and human

It is not FDA-approved

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Vitamin B 12 levels that are persistently elevated (greater than 1,000 pg/mL on two measurements) have been associated with solid tumors, hematologic malignancy, and increased risk of cardiovascular death

Patients who maintain adequate B12 during their program report better mood and better adherence