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According to the requestor, CRAO is a form of acute ischemic stroke which occurs when a vessel supplying blood to the brain is obstructed and there is growing recognition of this diagnosis as a vascular neurological problem

[PubMed 6341536] 915

In addition, NRF2 activity suppresses ROS production and directly reduces PGC-1, resulting in a lower expression level of mitochondrial genes [11]

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