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Moreover, nearly half of patients taking metformin with low or borderline vitamin B12 levels exhibited elevated homocysteine levels, suggesting a true tissue deficiency in vitamin B12 [2]

Acknowledgements We are grateful to the patients and their families who entrusted us with the care of their infants and to our colleagues caring for the patients

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First, virion assembly, like DNA replication, may be expected to involve primarily conserved viral protein-protein interactions, while entry is partly the result of interactions between viral entry mediators with -host receptor proteins