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Among these, CVDs represent the leading cause of mortality among the elderly ( Figure 1 In the cardiac environment, aging emerges as a stress response triggered by numerous stimuli, such as telomere attrition, virus infection, hypoxia, oxidative stress, mitochondrial dysfunction, protein imbalance, and impaired autophagy ( This manuscript discusses the phenotypic expressions and underlying molecular pathways correlated with the ageing process and their contribution to the development of CVDs

[DOI] [PubMed] [Google Scholar] 20.Foret MK, Lincoln R, Do Carmo S, Cuello AC, Cosa G

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When premature infants are born, their lungs are still in the growth stage, and hyperoxia causes poor lung development, increases death of alveolar epithelial cells, and triggers pulmonary vascular remodeling