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Effect and mechanism of astragaloside A on degenerative articular chondrocytes in human knee osteoarthritis (in Chinese)

We find that androgen excess primarily activates SLC1A5 expression

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Given that perturbations of the p53 locus occur frequently in severe/late stage endometriosis (25), downregulation of p53 expression may lead to the activation of the xCT-GPX4 pathway, promoting cell protection and survival by suppressing ferroptosis