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doi: 10.1016/s0162-0134(02)00406-3 109 BoonstraJPostJA

Anti-metastatic effect of metformin via repression of interleukin 6-induced epithelial-mesenchymal transition in human colon cancer cells

SLC1A5 promotes intracellular glutamine accumulation, which in turn increases leucine uptake via the SLC7A5 (LAT1) transporter, a process that is critical for activation of the mTORC1 signaling pathway via the Ragulator-Rag complex

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Intervention studies have shown that supplementation with riboflavin (the MTHFR cofactor) effectively lowers blood pressure, specifically in individuals with the variant MTHFR 677TT genotype

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