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[3] BPC-157 has been reviewed as a stable gastric pentadecapeptide with broad cytoprotective and tissue-repair activity in preclinical models, but this breadth of activity also makes receptor-based toxicology prediction less straightforward than it is for receptor-defined peptide drugs

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10.1016/j.jconrel.2014.07.042 127 PastushenkoI.BlanpainC

209 Furthermore, considerable evidence shows that obesity-associated adipocytes in pancreatic ductal adenocarcinoma can secrete IL-1 to attract tumor-associated neutrophils (TANs), which subsequently activate pancreatic stellate cells and contribute to tumor growth

Several hundreds of early SA-inducible genes were identified including two GSTs