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Colchicine: Colchicine has anti-inflammatory properties, but it may cause side effects, such as diarrhea

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In general, acetylcarnitine can also act as an antioxidant to reduce high levels of ROS in the mitochondria

However, it did not affect risk of heart failure or myocardial reinfarction [3][33]

Author contributions (I) Conception and design: FZ (II) Administrative support: FZ, FQ, JY (III) Provision of study materials or patients: FZ (IV) Collection and assembly of data: FZ, JY (V) Data analysis and interpretation: FZ, FQ, JY (VI) Manuscript writing: FZ, FQ, JY (VII) Final approval of manuscript: FZ, FQ, JY

Men with PD most commonly present in their sixth decade of life, with a mean age of 52-57 years old