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However, neither ePEs or ePCs containing PUFAs were enriched in non-NE cells in which ether lipid synthesis enzymes were upregulated, implying the importance of ether lipids in ferroptosis 137

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However, the p K a of the cysteine sulfhydryl side-chain is 8.4, and therefore, at intracellular pH ranges (7.07.4), these groups exist mostly in the non-nucleophilic thiol state