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Additionally, acteoside, a major active compound, has been reported to alleviate renal fibrosis and glycolipid metabolic disturbances by reducing oxidative stress and inflammation in -cells, modulating the unfolded protein response, improving mitochondrial dynamics, and enhancing -cell function and insulin secretion (69)

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10.1182/blood.v92.4.1191.416k15_1191_1198 [DOI] [PubMed] [Google Scholar] La Torre G., Calzoni L., Colamesta V., Guzzo A