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During this process, NH 3 is released and the lipoyl group of the H protein becomes reduced (dihydrolipoyl form)

Finally, to provide further proof that HuR controls KGA levels, we used the CRISPR-Cas9 knock-in system to modify the GLS gene by introducing a fluorescence protein (mKO2 49 ) within exon 19 to express KGA fused to mKO2 at its C-terminus (Fig

The treatment course is also constrained by the patients excretion efficiency

Acknowledgments The authors thank the Department of Orthopedic Surgery for the academic and administrative support

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and Y.D.) independently screened the titles and abstracts to identify and exclude studies not meeting the inclusion criteria