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Group V ( L

found that irisin-mediated p53 reduction decreases ferroptosis and protects cardiomyocytes against high-glucose injury by increasing SIRT1, decreasing p53 K382 acetylation to promote p53 degradation, and consequently upregulating SLC7A11 and GPX4 [108]

doi: 10.1161/CIRCHEARTFAILURE.113.000978 75 GaoZ.YinJ.ZhangJ.WardR

doi: 10.1016/j.redox.2024.103205 77 ChoYJParkSBHanM

Briefly, for each prediction the SHAP value of a particular variable is the difference in the model output when this variable is included versus when excluded

Lactobacillus plantarum -derived indole-3-lactic acid ameliorates colorectal tumorigenesis via epigenetic regulation of CD8 + T cell immunity
