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While ncRNAs play a major role in therapeutic resistance, they can function as regulated cell death (RCD) accelerators that modulate therapeutic sensitivity

Additional studies have demonstrated that the biologicals effects of thalidomide and IMiDs result from their binding to cereblon, which culminates in the ubiquitination and degradation of neo-substrates 47
Hydration during the absorption window (first 60 minutes post-injection) is critical

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