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Mitochondrial dysfunction is apparent as intramitochondrial iron deposition within the erythroid precursor, the hallmark ringed sideroblast. Mitochondrial cytopathy comprises a genetically heterogeneous group of disorders in which mitochondrial DNA shows deletions, duplications, and other mutations, of either sporadic or inherited origin (Fig

A multidisciplinary, patientcentered approach is essential to mitigate complications and improve quality of life

These data suggest that NRF2 activation following GSH depletion causes repression of LXR activity, leading to lower expression of lipogenic enzymes and lower levels of serum triglycerides

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Avoiding Common Reconstitution Pitfalls Over the years, we've compiled a list of common mistakes that can compromise research integrity
