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Importantly, although MenSCs exhibit strong migratory capacity due to high CXCR4 expression (Luz-Crawford et al., 2016), dysfunctional fibroblasts in diabetic wounds often fail to produce stromal cell-derived factor-1, thereby compromising MenSC homing efficiency (Mirzadegan et al., 2022

It's a vicious cycle

described a rare mutation in APP, near the Cys-rich domain, that generates an increase in A production related to a fast exit of APP from the endoplasmatic reticulum (ER) (Zhang et al., 2021)

Hileman EO

PMID: 39482885 Theranostics Energy competition remodels the metabolic glucose landscape of psoriatic epidermal cells

Neurosci 17(4) (1995) 20311