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Bile acids (BAs) Bile Acids (BAs) are another important actor in the modulation of the intestinal permeability and, thus, indirectly of low-grade systemic inflammation, both with a direct modulation of the intestinal barrier, and influencing the gut microbiota composition

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for review, see Sikiric et al., 2018) persists against the notion of continuous, direct injury (increased intra-abdominal hypertension) and shows that organs may adequately function despite continuously elevated intra-abdominal pressure