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The endpoint of B-cell receptor stimulation is the activation of the NF-B and MAP kinase pathways, which results in the proliferation, migration, and survival of CLL cells
The substitution of arginine (R537) with glutamine renders IRE-1 incapable of sensing LBS while sensing proteotoxic stress [49]
Weinberg JM
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Disturbed cingulate glutamate metabolism in adults with high-functioning autism spectrum disorder: Evidence in support of the excitatory/inhibitory imbalance hypothesis
Ubbink, 1994)
