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JD Hayes, JU Flanagan & IR Jowsey (2005) Glutathione transferases
When activated, this pathway orchestrates the transcription of numerous inflammatory genes, including those encoding TNF-, IL-1, IL-6, IL-12p40, and COX-2 [84]

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Additionally, it has beneficial effects on patients glycemic and blood pressure control, serum high-sensitivity C-reactive protein (hs-CRP) levels, total cholesterol/HDL cholesterol ratio, total cholesterol, and mental health parameters [209]
In animal models, age-related metabolic diseases and decline in healthspan can be mitigated by therapies that restore tissue levels of NAD [1-32], suggesting a role for NAD-boosting therapies [1-31]
PLoS ONE 6:e0025482
