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Further research is needed to determine whether eating foods rich in vitamin B12 or taking supplements can improve headaches

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Neuroprotective effects have been observed in certain models of neurological damage

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But only a maximum of 5mcg of B12 enters the bile every day (according to "Advanced Haematology" 7th edition textbook, page 60), so it seems that only an additional 5mcg would be lost daily if none was recovered