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Intra-articular delivery of an AAV-anti-TNF- vector alleviates the progress of arthritis in a RA mouse model
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Glutathion inhibits melanin formation (pigment material of skin) by quenching free radicals and peroxides that contribute to tyrosinase activation and melanin formation

Histamine receptors are markedly expressed in striatum, suggesting histamine has an important role in modulation of this circuit (Bolam and Ellender, 2016
Another option is to use compounds that can form nontoxic complexes with Cu (II), preventing its accumulation in senile plaques and increasing its bioavailability
