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MTHFR gene mutations affect our health in many ways: C667T and A1298C mutations may lower blood folate concentration, requiring more than the normal daily suggested amount of 400 micrograms
Vitamin B12 is essential to maintain nervous system integrity and promote red blood cell synthesis
The reduced binding protein affinity also means more free IGF-1 LR3 remains available to interact with target tissues
Applied Microbiology and Biotechnology, 102(23), 1010310117
Therefore, we could have chosen any percentage within the 40% to 100% range to represent the average estradiol in females
