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Low catalase levels in the epidermis of patients with vitiligo

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Catalase does not show significant activity under physiological conditions due to its lower affinity than glutathione peroxidase for hydrogen peroxide, but becomes an important enzyme at disease state where concentration of H 2 O 2 is elevated [47]

Harzallah F, Alberti H, Ben Khalifa F

Moreover, Treg cells can restrict CD4 + T cell overactivation and its dysfunction is involved in SLE pathogenesis (5961)

Paraquat induced oxidative stress, DNA damage, and cytotoxicity in lymphocytes