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1 Although T4 is solely synthesized by the thyroid gland, a large proportion of T3 or reverse T3 (rT3) is produced as metabolically active or inactive forms of thyroid hormone, respectively, in peripheral organs including the kidney

Table 1 Multi-weaponry approach involving glutathione (GSH) enhancers, nuclear factor erythroid 2 p45related factor 2 (Nrf2) activators, toll-like receptor (TLR) inhibitors/immunomodulators, C-reactive protein (CRP) level reduction, natural and immune immunoglobulin M (IgM) enhancement and immune cell function recovery against SARS-CoV-2 infection and COVID-19 disease

Cohen SM, Arnold LL

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Demonstration of 26-hydroxylation of C27-steroids in human skin fibroblasts, and a deficiency of this activity in cerebrotendinous xanthomatosis