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In a phase 2 clinical study, patients who were administered 20 mg/day lorcaserin attained an average weight loss of 3.6 kg, which was significantly greater than the average weight loss of 0.3 kg in the placebo group [82]
Thus, GSH supplementation in the DG sub-group of elderly diabetic patients over a period of 6 months led to a significant increase in the erythrocyte GSH, GSSG, and FPI and a decrease in HbA1c and 8-OHdG levels (Figure S2), suggesting that the elderly diabetic population responds better to GSH supplementation in conjunction with anti-diabetic therapy
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