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In addition, it has been proposed that the oxidative damage induced by ROS induces a tissue-specific reduction of the TL, which is derived from the antioxidant capacity of each tissue [116,117]

This can have visible impacts in terms of skin appearance, resulting in reduced age spots and wrinkles, and can help to prevent acne breakouts and inflammatory skin flare-ups

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

Ge MH, Tian H, Mao L, Li DY, Lin JQ, Hu HS et al (2021) Zinc attenuates ferroptosis and promotes functional recovery in contusion spinal cord injury by activating Nrf2/GPX4 defense pathway

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Neurochem Res 37:25692588 Diaz Vivancos P, Wolff T, Markovic J, Pallardo FV, Foyer CH (2010) A nuclear glutathione cycle within the cell cycle