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Simultaneously, PDT triggers acute inflammation and activates both innate and adaptive immunity, inducing damage-associated molecular patterns (DAMPs) (187, 188)

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It binds to multiple melanocortin receptor subtypes, but its primary effects come through two: MC1R (Melanocortin-1 Receptor) expressed on melanocytes in the skin

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This reaction is similar to the first-round reaction, in which acetyl-ACP condenses with malonyl-ACP to form a C 4 --ketoacyl-ACP

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