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Effect of osmotic stress on glutathione and hydroxymethylglutathione accumulation in wheat

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However, this analysis did not specifically address CRC-associated metabolic adaptations or resistance mechanisms

Mechanistically, L-DON and JHU-083 suppressed tumor glutamine metabolism by inhibiting all the glutamine-utilizing enzymes, and simultaneously suppressed tumor glycolysis by activating AMP Kinase (AMPK) and inhibiting the expression of c-MYC [114, 115]