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As the master antioxidant in the body Glutathione has a range of divers metabolic functions including acting as a free radical scavenger, "recharging" depleted antioxidants back into their active state (Vitamin C, Vitamin E, Vitamin A, etc.), maintaining the immune system, supporting protein structures and removing heavy metals such as mercury through the liver

doi: 10.1371/journal.ppat.1007049 77 CiudadS.PuigE.BotzanowskiT.MeigooniM.ArangoA

(7-10) Glutathione and related enzymes play a crucial role in defending the body against oxidative stress

Maturational loss of the vitamin C transporter in erythrocytes

Here we demonstrated that whereas GPx7 preferentially oxidized ERp46 and ERp72 in vitro, the enzyme bound PDI and P5 in H 2 O 2 -treated cells