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doi: 10.1016/j.cyto.2007.04.006 132 WangHBiCWangYSunJMengXLiJ

The activation of sirtuins, proteins strongly associated with longevity, provides additional anti-aging benefits

The former is accompanied by extensive edema, resulting in an abnormal cardiovascular system, circulatory failure and heart attack, while the latter is associated with abnormal functioning of the nervous system and the development of polyneuropathy and Wernickis encephalopathy

Indeed, Grx3 is overexpressed in breast cancer tissue [208] and in breast adenocarcinoma malignant phenotypes in human samples [209]

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