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In oncology, clinical trials show promise with ASOs for malignant glioblastoma and pancreatic cancer, antibodies for metastatic melanoma and renal cell carcinoma, and chemical inhibition for glioblastoma, as well as augmentation of tumour vaccines for non-small-cell lung cancer

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Otherwise, reported side effects were similar to other vaccines and included injection site pain, rash, headaches, and muscle soreness

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A recent proteomics-based study has revealed that NNMT is a main metabolic regulator of CAFs in ovary cancer (74)