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[DOI] [PMC free article] [PubMed] [Google Scholar] 99.Urrutia P.J., Mena N.P., Nunez M.T

Furthermore, the changes in the electron configuration of the metal cations before and after chelate reaction revealed that Cu 2+ , Ni 2+ ,Co 2+ and Hg 2+ had obvious tendencies to be reduced to Cu + ,Ni + ,Co + and Hg + during the coordination process

If an antioxidant is not present in sufficient quantity to neutralize ROS, oxidation of biomolecules, like lipid peroxidation, protein damage (carbonylation of aminoalkanoic acid residues), oxidation of single DNA and RNA nucleotides, enzyme inhibition, and activation of apoptosis, will occur (Gill and Tuteja, 2010)