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Reasoning that the enzymes encoded by these genes could be responsible for the utilization of l-carnitine and its conversion to BB (Figure 7C), we used comparative genomics tools to identify 3 other organisms that contain the caiTABCDE gene operon (Supplemental Figure 5), and assessed their ability to consume l-carnitine and produce BB (Figure 8)

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The unfolded protein response and chemical chaperones reduce protein misfolding and colitis in mice

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Although today several studies have investigated the mechanism involved in metabolic plasticity, but key pathway has not been identified which could be considered a unique target for cancer therapy

International agency for research on cancer monograph working group