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Nie, J., Lin, B., Zhou, M., Wu, L
In mammals, OS arises from either an overproduction of ROS or a reduction in antioxidant defense mechanisms [6]

598 FTH1 knockdown in neurons significantly inhibits cell viability and causes mitochondrial dysfunction, while overexpression of FTH1 impairs ferritinophagy, downregulates the expression of LC3 and NCOA4, and finally inhibits cell ferroptosis

Yet the very treatment that is supposed to protect the liver can also end up straining it insteadcausing real harm
Vyoral D, Jiri P

Gupta I, Badrzadeh F, Tsentalovich Y, Gaykalova DA
