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Although NQO1 is not as studied in the field of MASLD, the studies that have been conducted to date have shown varying results regarding the expression and/or activity of this enzyme in MASLD/MASH patients as well as in many MASLD/MASH animal or cell models (Table S6)

Paradoxically, the redox activities of ROS and RNS play critical roles in cell signaling and exercise adaptation, a phenomenon summarized by the concept of hormesis, where low levels of stress promote adaptation to and thus protection from, subsequent stress [12]

Human umbilical cord mesenchymal stem cells in diabetes mellitus and its complications: applications and research advances