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Virtual Screening, ADMET Prediction, Molecular Docking, and Dynamic Simulation Studies of Natural Products as BACE1 Inhibitors for the Management of Alzheimer's Disease. Scientific Reports 14: 26431

However, Hara et al
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Simultaneously, multi-omics technologies including genomics, transcriptomics, proteomics, and metabolomics should be integrated to deeply analyze curcumins mechanism of action within complex disease networks, particularly its synergistic effects with other molecules or pathways

conducted a single-center, randomized, double-blind, controlled trial with an LOE of 2b and 48 controls receiving 4 g of LC or placebo daily
