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Cell Metab 12:509520

Resistance training increases muscle NAD+ and NADH concentrations as well as NAMPT protein levels and global sirtuin activity in middle-aged, overweight, untrained individuals

3 Yu JT, Xu W, Tan CC, Andrieu S, Suckling J, Evangelou E, Pan A, Zhang C, Jia J, Feng L, Kua EH, Wang YJ, Wang HF, Tan MS, Li JQ, Hou XH, Wan Y, Tan L, Mok V, Tan L, Dong Q, Touchon J, Gauthier S, Aisen PS, Vellas B

For example, older people (because absorption declines with age) and those with gut-related conditions such as celiac disease and Crohns disease may struggle to absorb enough vitamin B12 to stave off symptoms of a deficiency, says Foxx

1 Vannini F, Di Matteo B, Filardo G, Kon E, Marcacci M, Giannini S

This is hypoxia-induced oxidative stress