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Based on the above, it is known that DNMTs with DNA methyltransferase activity mainly include DNMT1, DNMT3a and DNMT3b, and BaP further affects genome-wide or specific gene methylation levels by increasing DNMT1 expression or decreasing DNMT3a expression [71, 152]

When to seek medical attention : Patients experiencing persistent unexplained tiredness lasting more than a few weeks, particularly when accompanied by any neurological symptoms such as numbness, tingling, or balance problems, should consult their GP

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The stress response system also comes under DSIPs influence