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Pro-caspase-1, contained in CARD, catalyzes to its active form and leads to the production of proinflammatory cytokines interleukin (IL)-1 and IL-18 and to cleavage of gasdermin D, thereby producing pores in the cell membrane and promoting pyroptotic cell death [163], which associates release of DAMPs [164]

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Mechanisms underlying curcumin-induced neuroprotection in cerebral ischemia

Fragile X mental retardation protein: nucleocytoplasmic shuttling and association with somatodendritic ribosomes

[1] [4] Mood changes including low mood, irritability, or anxiety can be associated with declining B12 levels, though these symptoms are non-specific and can have many causes