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AOD-9604 (Advanced Obesity Drug peptide) is a research-grade peptide derived from the C-terminus of human growth hormone (HGH), specifically the 176191 amino acid sequence

CD38 inhibition to reduce NAD+ consumption CD38 breaks down NAD+ and becomes more active as we age due to inflammation

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Secondary metabolic markers include fasting glucose, insulin sensitivity via HOMA-IR or glucose tolerance testing, body composition changes (DEXA scan or MRI for fat mass and lean mass distribution), mitochondrial respiration capacity via Seahorse analyzer, and serum markers like HbA1c for long-term glucose control

Castle WB, Ross JB, Davidson CS, Burchenal JH, Fox HJ, Ham TH