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[DOI] [PMC free article] [PubMed] [Google Scholar] 206.De Nuccio F., Cianciulli A., Porro C., Kashyrina M., Ruggiero M., Calvello R., Miraglia A., Nicolardi G., Lofrumento D.D., Panaro M.A

According to a long-term outcomes study in The Lancet (PubMed) , a significant proportion of patients with chronic sciatica who did not receive surgical intervention continued to report sciatica pain at one and two years, highlighting the importance of timely specialist evaluation

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The animal experiments were also conducted in accordance with relevant guidelines and regulations

In contrast, retinol and -tocopherol are lipophilic and may neutralize free radicals that damage the cell membrane and its constituent parts

These astrocytes are, however, the preferential site for glucose uptake from the blood, as well as having projections in peri-synaptic areas of neurons, providing close interaction with neuronal elements and acting as a cellular barrier between blood and neurons