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The PAG and SN are both located in the midbrain, with evidence for bidirectional connectivity between these regions [59, 60]

10.3390/md9081307 46 ChengS
Ramos-Jimnez A, Hernndez-Torres RP, Hernndez-Ontiveros DA, Ortiz-Ortiz M, Lpez-Fregoso RJ, Martnez-Sanz JM, Rodrguez-Uribe G, Hernndez-Lepe MA

doi: 10.1016/j.cellsig.2010.11.015

10.1016/j.tcb.2015.12.007 335 WannametheeS
Other studies have also described a similar mechanism involving the inhibition of human immunodeficiency virus type 1 (HIV-1)
