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As long as 60 years ago, identification of the alternative IF-independent mechanism for vitamin B 12 absorption resulted in the discovery that if large enough doses were given, in the range of 100-100,000 g (although only 1% of the cyanocobalamin was absorbed), it was sufficient to provide the daily requirement

The American Society for Metabolic and Bariatric Surgery recommends that patients who have had bariatric surgery take 1 mg of oral vitamin B 12 per day indefinitely

It is a partial sequence of a body protection compound discovered in and isolated from human gastric juice

Lower hormone effectiveness may result in underdosing and affect treatment outcomes

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