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For instance, iron overload induced by ferric ammonium citrate significantly enhances chondrocyte apoptosis and increases the expression of matrix metalloproteinases (MMP3, MMP13) (Jing et al., 2021a)

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Dopaminergic neuronal loss in the substantia nigra pars compacta (SNpc) is a well-known feature of PD

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The mutation of NA leads to a variety of drug resistance mechanisms