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doi: 10.5582/irdr.2018.01055

Ferroptosis, coined by Stockwell's group in 2012, designates a specific non-apoptotic cell death caused by such accumulation of lipid peroxides following cystine deprivation (42)

However, despite these findings, the precise enzymes and mechanisms involved in lactylation regulation in cells remain unknown, highlighting the need for further research in this area

However, high-dose purified EPA formulations (4,000 mg/day EPA alone) were associated with a 50% relative increase in bleeding events, though this translated to a modest absolute risk increase of only 0.6% (247)

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