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Retrieved 23 July 2018

Some researchers believe that GIP receptor activation partially offsets the nausea caused by GLP-1 stimulation, which could explain why some patients tolerate tirzepatide better than pure GLP-1 agonists despite receiving more potent appetite suppression

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112 A meta-analysis of observational studies (n = 21 837 people 1290 years old) revealed a significant inverse association between dietary intake of vitamin B 12 and/or vitamin B 12 supplementation and the risk of depression in women