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doi: 10.1038/s41598-021-81774-8 96 YouZPZhangYLShiKShiLZhangYZZhouYet al

Trends Immunol (2015) 36(1):312

Alterations of the UPS, which render them more or less susceptible to degradation, are responsible for disorders of renal diseases

Moskowitz A, Donnino MW

There are many different modes of polymer degradation

REDEFINE 1 and REDEFINE 2 ran 68 weeks, with the first ~16 weeks dedicated to dose titration
