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10.1111/jpi.12018 84

The SURMOUNT-1 clinical trial showed that participants on 15 mg of tirzepatide lost an average of 22.5% of their body weight over 72 weeks
Whilst ROS can contribute to the onset of fatigue, there is increasing evidence that they play a crucial role in exercise adaptations

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Clinical trial NCT04050670 examined tirzepatide absorption at different sites and found something interesting

The results showed that the OD570 value significantly increased, the intracellular Bcl-2 protein expression level was significantly elevated and the Bax, cleaved caspase-3 protein expression levels and apoptosis rate significantly decreased
