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Table 1 summarizes the effects of the main flavonoids explored in this section, highlighting the main dietary sources, mechanisms of action described in preclinical studies and clinical trials/studies in humans with doses used, if pertinent

The last century witnessed seminal discoveries of ion channels that explained neuronal excitability, information processing, and plasticity, leading to the predominance of neuron-centric views in neurology, psychiatry and neuropharmacology